Madotsuki's Story/guide

Complete (Version 1.4.3)

Guitar
Enter the green door. Go left and interact with Pirori.

Black Rose
Enter the wooden door. Go right and interact with Monoe.

Biscuit
(Black Rose effect is needed).

Enter the blue and white door. Use the Black Rose effect to jump/hover over the blocks and go north-east. Get up onto a platform with a large cup on it then hover up and to the left until you disappear off-screen and you seem to be moving along a row of blocks.

Move to the left until you appear on screen again. Go left and interact with the biscuit.

Megane
Enter the blue and white door. Use the Black Rose effect to jump/hover over the blocks and go east, use Bisquit effect on Kamakurako, use Black Rose effect to fly over the Toriningen and while equipping by guitar interact with the Pirori to get effect.

Roller Skates
Enter the wooden door. Go right and using Megane effect interact with Monoe, after a "familiar event" go right and using Megane effect interact with Monoko to get effect.

Doll
Enter the wooden door. Go right and using Megane effect interact with Monoe, after a "familiar event" go right and using Black Rose effect interact with Monoko, in next area if crate hanging on the rope wake up and repeat same actons, then using Megane effect interact with Mafurako to get new effect.

Pain
Enter the blue and white door. Use the Black Rose effect to jump/hover over the blocks and go east, use Bisquit effect on Kamakurako, use Black Rose effect to fly over the Toriningen and while equipping by Doll effect interact with the Pirori then enter the hall in the wall, interact with the Kyuku-kun to get last effect.

Ending
After collecting all effects enter the first door in nexus, go right and using Pain effect kill Poniko and then kill Uboa, (press a button to stab them, do this until small scene with Akumu aka Bloody Touching Monster from Uboa's Trap.), after forcing awakening, leave Mado's room through the opened door to see ending.

Unlocking Nasu? Mini-Game
Use Black Rose effect and fly in left upper corner, enter the door on the cloud, go right and use Pain effect kill the doll on the table. you will get game cartridge take it and wake up, interact with the game console in Mado's room, game now in your full disposal, just interact with console to play it.